Clément Perrot

2024

Cellular coordination

Section of mouse cerebellum - Confocal microscopy

Using confocal microscopy, Clément Perrot reveals a thin section of the cerebellum, a little-known region of the brain essential to the fluidity and precision of our movements.

The large cyan cells are the Purkinje cells, the conductors of movement. They integrate signals from the body in real time to adjust each action.
Around them, myelin, colored magenta, forms a protective sheath around nerve fibers, accelerating the transmission of impulses like a fluid, well-rehearsed score.

Together, these structures compose a silent cellular symphony, making every step, every word, every movement possible.

In multiple sclerosis, this orchestration is disrupted: myelin degrades, signals are scrambled.
By visualizing this organization with such finesse, researchers hope to better understand the disease... and find ways to restore lost harmony.

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