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2023
In this luminous work, Marina Maletic invites us to immerse ourselves in a miniature brain, grown in the laboratory from the cells of patients. This reduced model, known as a cerebral organoid, enables us to reproduce the first stages of human brain development, not in an animal, but in a living tissue fashioned from our own material.
Here, colors tell a story: healthy cells, in red, coexist with mutated cells, in green, from patients suffering from a severe form of epilepsy resistant to treatment. Under the lens, early disorganizations appear, previously invisible, revealing the cellular origins of seizures.
By observing this faulty organization, researchers can identify the mechanisms responsible for the disease... and test new therapies, directly on human tissue, in an ethical and targeted way.
These images embody a silent revolution: understanding diseases as close as possible to their origins, predicting the effect of treatments, and perhaps one day, repairing the very architecture of thought.
